+353 (0)21 2346833
sofia.teixeira (at) tyndall (dot) ie
My research focus is the development of novel nanosensors for the detection of disease associated biological molecules. Working within the Tyndall National Institute, my research involves molecular and cell biology techniques together with high-resolution material fabrication, functionalization and characterisation to develop next generation biosensors.
Physical, biochemical and biological characterisation of the sensor platforms is achieved with a number of techniques such as: Ultra violet and electron-beam lithography, chemical etching, physical vapour deposition (PVD) and rapid thermal annealing for fabrication. High-resolution characterisation tools such as Autolab (electrochemical), Scanning Electron Microscopy, Raman Spectrosocpy and Atomic Force Microscopy are also used in conjugation with biological techniques such as quantitative PCR, chromatin Immunoprecipitation, Methylated DNA immunprecipitation and enzyme-linked immunosorbent assay’s. With the aim of meeting the clinical need for rapid, simple and accurate diagnostics tests, my research is undertaken with clinical context in mind. In the short-term this involves adapting immune-based capture methods to microfluidic devices, whilst longer term goals will focus on multiplex platforms and novel recognition technologies.
Funder | Start Date | End Date | Title | Role |
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Enterprise Irl | 27-AUG-20 | 26-AUG-21 | Novel Electrochemical Sensor for Point of Care Diagnosis | Principal Investigator |
Company | Country | Name |
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Swansea University | UNITED KINGDOM | Sonia Consuegra |
University of Aveiro | PORTUGAL | Florinda Costa |
Wales Fertility Institute Singleton Hospital | UNITED KINGDOM | Nadja Melo |
Tyndall National Institute | IRELAND | Daniela Iacopino |
Year | Journal | Publication |
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2020 | Molecular Ecology | Environmental enrichment induces intergenerational behavioural and epigenetic effects on fish Berbel, WM;Berry, N;Rodriguez-Barreto, D;Teixeira, SR;de Leaniz, CG;Consuegra, S (2020) Environmental enrichment induces intergenerational behavioural and epigenetic effects on fish. : WILEY. [Details] |
2020 | Biosensors & Bioelectronics | Non-invasive molecular assessment of human embryo development and implantation potential. Abreu CM;Thomas V;Knaggs P;Bunkheila A;Cruz A;Teixeira SR;Alpuim P;Francis LW;Gebril A;Ibrahim A;Margarit L;Gonzalez D;Freitas PP;Conlan RS;Mendes Pinto I; (2020) Non-invasive molecular assessment of human embryo development and implantation potential.. : . [Details] |
2019 | Biosensors & Bioelectronics | Direct monitoring of breast and endometrial cancer cell epigenetic response to DNA methyltransferase and histone deacetylase inhibitors. Teixeira SR;Abreu CM;Parkes L;Davies J;Yao S;Sawhney MA;Margarit L;Gonzalez D;Pinto IM;Francis LW;Conlan RS; (2019) Direct monitoring of breast and endometrial cancer cell epigenetic response to DNA methyltransferase and histone deacetylase inhibitors.. : . [Details] |
2019 | ACS applied materials & interfaces | Physical Structure and Electrochemical Response of Diamond-Graphite Nanoplatelets: From CVD Synthesis to Label-Free Biosensors. Santos, Nuno; Pereira, Sónia; Fernandes, António; Vasconcelos, Thiago; Fung, Chung Man; Archanjo, Braulio; Achete, Carlos; Teixeira, Sofia Rodrigues; Silva, Rui; Costa, Florinda. (2019) Physical Structure and Electrochemical Response of Diamond-Graphite Nanoplatelets: From CVD Synthesis to Label-Free Biosensors.. : . [Details] |
2019 | Electrochemistry Communications | Measuring the impact on impedance spectroscopy of pseudo-reference electrode accumulations Sawhney M.;Azzopardi E.;Rodrigues Teixeira S.;Francis L.;Conlan R.;Gazze S. (2019) Measuring the impact on impedance spectroscopy of pseudo-reference electrode accumulations. : . [Details] |
2018 | Analytical Biochemistry | Ultrasensitive environmental assessment of xeno-estrogens in water samples using label-free graphene immunosensors. Barton H;Berbel-Filho WM;Consuegra S;Francis L;Tizaoui C;Conlan RS;Teixeira SR; (2018) Ultrasensitive environmental assessment of xeno-estrogens in water samples using label-free graphene immunosensors.. : . [Details] |
2017 | Journal Of Controlled Release | Chromophores in operative surgery: Current practice and rationalized development. Azzopardi EA;Owens SE;Murison M;Rees D;Anne Sawhney M;Francis LW;Sofia Rodrigues Teixeira R;Clement M;Steven Conlan R;Whitaker IS; (2017) Chromophores in operative surgery: Current practice and rationalized development.. : . [Details] |
2016 | Journal of Surgery | Clinical applications of amylase: Novel perspectives. Azzopardi E;Lloyd C;Teixeira SR;Conlan RS;Whitaker IS; (2016) Clinical applications of amylase: Novel perspectives.. : . [Details] |
2016 | Biosensors & Bioelectronics | Polyaniline-graphene based α-amylase biosensor with a linear dynamic range in excess of 6 orders of magnitude. Teixeira SR;Lloyd C;Yao S;Andrea Salvatore Gazze ;Whitaker IS;Francis L;Conlan RS;Azzopardi E; (2016) Polyaniline-graphene based α-amylase biosensor with a linear dynamic range in excess of 6 orders of magnitude.. : . [Details] |
2014 | Electroanalysis | Chitosan/AuNPs Modified Graphene Electrochemical Sensor for Label-Free Human Chorionic Gonadotropin Detection Teixeira S., Ferreira N. S., Conlan R S., Guy O. J., M. Goreti F. Sales (2014) Chitosan/AuNPs Modified Graphene Electrochemical Sensor for Label-Free Human Chorionic Gonadotropin Detection. : . |
2014 | Sensors and Actuators, B: Chemical | Epitaxial graphene immunosensor for human chorionic gonadotropin Teixeira, S;Burwell, G;Castaing, A;Gonzalez, D;Conlan, RS;Guy, OJ (2014) Epitaxial graphene immunosensor for human chorionic gonadotropin. : ELSEVIER SCIENCE SA. [Details] |
2014 | Electrochimica Acta | Novel single-wall carbon nanotube screen-printed electrode as an immunosensor for human chorionic gonadotropin Teixeira, S;Conlan, RS;Guy, OJ;Sales, MGF (2014) Novel single-wall carbon nanotube screen-printed electrode as an immunosensor for human chorionic gonadotropin. : PERGAMON-ELSEVIER SCIENCE LTD. [Details] |
2014 | Journal of Materials Chemistry B | Label-free human chorionic gonadotropin detection at picogram levels using oriented antibodies bound to graphene screen-printed electrodes Teixeira, S;Conlan, RS;Guy, OJ;Sales, MGF (2014) Label-free human chorionic gonadotropin detection at picogram levels using oriented antibodies bound to graphene screen-printed electrodes. : ROYAL SOC CHEMISTRY. [Details] |
2013 | Total Quality Management & Business Excellence | Food safety management system implementation and certification: survey results Teixeira, S;Sampaio, P (2013) Food safety management system implementation and certification: survey results. : ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD. [Details] |
Year | Publication |
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2013 | Hetero-SIC-WASMPE13 Burwell G., Teixeira S., Castaing A., Guy O. (2013) Hetero-SIC-WASMPE13. : . |
2011 | Institute of Industrial Engineers Annual Conference Teixeira, S., Sampaio, P. (2011) Institute of Industrial Engineers Annual Conference. : . |
Year | Publication |
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2020 | 71st Annual Meeting of the International Society of Electrochemistry Sofia Rodrigues Teixeira and Paul Galvin (2020) 71st Annual Meeting of the International Society of Electrochemistry. : . |
2020 | 2nd Symposium on Welfare in aquaculture Sofia Teixeira (2020) 2nd Symposium on Welfare in aquaculture. : . |
2019 | ISSC-22 Interdisciplinary Surface Science Conference Sofia Rodrigues Teixeira and Paul Galvin (2019) ISSC-22 Interdisciplinary Surface Science Conference. : . |
2018 | Cambridge Healthtech Institute’s Sixth International Molecular Diagnostics Europe Sofia Teixeira, Lewis Francis, Steve Conlan (2018) Cambridge Healthtech Institute’s Sixth International Molecular Diagnostics Europe. : . |
2018 | Oriel Science: Showcasing science in the community Sofia Teixeira (2018) Oriel Science: Showcasing science in the community. : . |
2018 | International Conference on Nanomedicine and Nanobiotechnology – ICONAN 2018 Teixeira, S., L. Parkes, L. W. Francis, Conlan, R. S. (2018) International Conference on Nanomedicine and Nanobiotechnology – ICONAN 2018. : . |
2017 | 7th International Congress Nanotechnology in Biology & Medicine Teixeira, S., Pinto, I. Conlan, R. S. (2017) 7th International Congress Nanotechnology in Biology & Medicine. : . |
2015 | 12th International Conference on Nanosciences & Nanotechnologies (NN15) Teixeira, S., Conlan, R.S. (2015) 12th International Conference on Nanosciences & Nanotechnologies (NN15). : . |
2013 | Imaginenano2013 Teixeira, S., Castaing, A., Burwell, G., Conlan, R.S., Guy. O.J. (2013) Imaginenano2013. : . |
2019 - Current Advanced Electrochemistry course, Electroanalytical Chemistry (CM4027/CM6013) University College Cork Department of Chemistry, Ireland
2016 - 2018 Colloids module, MEng Chemical Engineering (EGDM01) Swansea University College of Engineering, United Kingdom
2015 - 2018 Diagnostics and Imaging course of the Nanomedicine Maters studies (PMNM02) Swansea University Medical School, United Kingdom
2015 - 2018 Diagnostics and Imaging course of the Nanomedicine Maters studies (PMZM13) Swansea University Medical School, United Kingdom
2015 - 2016 Wastewater treatment of the Civil Engineering Maters studies (EG-401) Swansea University College of Engineering, United Kingdom